GM1 Prophylaxis for Post-chemotherapy Cognitive Impairment in Patients With Early Operable Breast Cancer

Inclusion Criteria

• •1. Have provided written and signed informed consent;
• •2. Histologically confirmed invasive ductal carcinoma;
• •3. Planned to received (neo)/adjuvant chemotherapy;
• •4. Eastern Cooperative Oncology Group (ECOG) score of 0 to 1;
• •5. Can cope with HVLT-RDR and ADAS-Cog evaluation;
• •6. No prior therapy could induce neurological damage,within 4 weeks
• •7. Normal blood routine, liver and kidney functions within 1 week before enrollment in this study;
• •8. Women of childbearing age have a negative serum or urinary pregnancy tests prior to enrollment in this study; Pre-menopause women are contracepted with medically acceptable methods during the study period.
• •9. Compliance with the study protocol.