Placebo Controlled Efficacy Evaluation of the Hydrolyzed Collagen Peptide In Adult Females

Exclusion Criteria

• •Who have atopic constitution or asthma and/or known allergy for biosynthetic collagen products and/or other any of the excipients of the product.
• •Who have hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.
• •Who have the use of oral retinoids or oral steroids in the 6 months prior to initiation of the study.
• •Who have the use of topical retinoids, anti-wrinkle cosmetic products including retinol and/or AHA, or moisture-rich cosmetic products within the 3 months prior to initiation of the study.
• •Who use skincare therapy using lasers or peeling within the 3 months prior to initiation of the study.
• •Who have current participation in another clinical study, or participation in any type of dermatology study within 3 months.
• •Who have any history or presence of clinical relevance of cardiovascular, neurological, musculoskeletal, haematological, hepatic, gastrointestinal, renal, pulmonary, endocrinological, metabolism or psychiatric disease, any type of porphiria.
• •Who have the presence or history of malabsorption or any gastrointestinal surgery except appendectomy or except herniotomy.
• •Who had undergone, or planned to undergo, pregnancy or breastfeeding.
• •Who have current intake of contraceptives, female hormones, obesity drugs, absorption inhibitors, antidepressants, or appetite suppressants.
• •Who are suspected to have a high probability of non-compliance to the study procedure and/or completion of the study according to the investigator's judgment.
• •Who have history of drug abuse.
• •Who have relationship to the investigator.