Age

18–75

Sex

ALL

Healthy volunteers

Not accepted

Age:18-75 years
Pathologically diagnosed advanced (stage IV) malignant melanoma, bladder cancer or colorectal cancer with measurable lesions;
Failed in the previous standard therapy;
ECOG PS (Eastern Cooperative Oncology Group performance status) score 0-2 points;
The estimated survival period is ≥3 months;
Rehabilitate from previous therapy;
Adequate organ functions;
Patient's written informed consent;

Personalized Immune Cell Therapy Targeting Neoantigen of Malignant Solid Tumors