A Novel Argon Laser Iridoplasty for Pigment Dispersion Syndrome

\*Study design: Interventional, longitudinal, prospective, uncontrolled case series study \*\*Methods: * Population: cases of pigment dispersion syndrome/glaucoma. * Sample size: Not determined since it is a case series with still active recruitment. * A series of pigment dispersion syndrome and/or pigment dispersion glaucoma cases encountered in the ophthalmology outpatient clinic of Fayoum University Hospitals will be assessed clinically for confirmation of signs of pigment dispersion by slitlamp examination and gonioscopy. Intraocular pressure will be measured and monitored. Fundus examination with special attention to the optic disc will be done. Cases will be assessed prior to iridoplasty by anterior segment optical coherence tomography to document the anomalous iris configuration with subsequent serial anterior segment OCT at one week, one month and three months after iridoplasty as well as IOP measurement. * The iridoplasty procedure will be performed as follows: 1. Pilocarpine 2% topically is used to induce miosis. 2. Topical ocular anesthetic is instilled. 3. The Nidek Argon laser device together with a YAG capsolutomy or Abraham Iridotomy lens as auxilliary lenses are used. 4. The site and parameters of argon laser applications on the anterior iris surface are tailored for each patient according to iris configuration and pupil diameter in mesopic conditions determined by anterior segment OCT. 5. Topical Brimonidine 0.2% bid is used for one week after the procedure to guard against IOP spikes.