Age

18–any

Sex

FEMALE

Healthy volunteers

Not accepted

Age: 18 years or older
Histologically confirmed diagnosis of invasive breast carcinoma (biological immunohistochemical profile: luminal and/or human epidermal growth factor receptor 2 positive)
Distant metastatic disease not progressing after 6 months of systemic therapy
Zubrod Performance status of 0-1
Unifocal tumour \< 5 cm tumor size
Tumor CT or 18-labeled fluorodeoxyglucose positron emission tomography (5FDG-PET) detectable
No surgery being recommended at time of enrollment.

prior radiotherapy
active systemic lupus erythematosus, or any history of scleroderma, dermatomyositis with active rash
Women who are pregnant or lactating.
Psychiatric or addictive disorders that preclude obtaining informed consent or adherence to protocol

Breast Stereotactic Radiotherapy to Primary Tumors in Metastatic Patients