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Post-menopausal females experience elevated cardiovascular disease risk (CVD), compared to premenopausal females and age-matched males. Current exercise guidelines appear inadequate to ameliorate this increased risk and higher intensity exercise may be necessary. Oral inorganic nitrate supplementation enhances both exercise performance and CVD risk profile in several clinical conditions. However, the effects of this intervention in post-menopausal females is unexplored.
The purpose of this study is to determine whether acute inorganic nitrate supplementation and exercising at different exercise intensities (high vs moderate) improve vascular health in post-menopausal females.
Age
45 - 75 years
Sex
FEMALE
Healthy Volunteers
Yes
Student Health and Wellness Center
Charlottesville, Virginia, United States
Start Date
November 1, 2021
Primary Completion Date
April 1, 2023
Completion Date
April 1, 2023
Last Updated
November 30, 2023
24
ACTUAL participants
BEET IT - Concentrate Beet root juice
DRUG
BEET IT - Concentrate Beet root juice (nitrate depleted)
DRUG
Lead Sponsor
University of Virginia
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT06817252