About Pricing FAQs Blog

Loading clinical trials...

Your health journey, clearly organized.

Find Clinical Trials →

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

RECRUITINGNA

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

Hyperhydration to Improve Kidney Outcomes in Children With Shiga Toxin-Producing E. Coli Infection: A Multinational Embedded Cluster Crossover Randomized Trial

NCT05219110•University of Calgary

View on ClinicalTrials.gov

AI summary by Clareo Health

Generating AI summary...

Conditions

Shiga Toxin-Producing Escherichia Coli (E. Coli) InfectionHemolytic-Uremic Syndrome

Interventions

Infusion of 200% maintenance fluids as balanced crystalloid IV solution

Oral fluids; infusion of up to 110% maintenance fluids as balanced crystalloid IV solution

Locations

26

United States

Locations (26)

University of Alabama at Birmingham

Birmingham, Alabama, United States

Arkansas Children's Hospital

Little Rock, Arkansas, United States

University of California, San Diego

La Jolla, California, United States

University of California, Davis

Sacramento, California, United States

University of Colorado Denver

Denver, Colorado, United States

Children's Research Institute

Washington D.C., District of Columbia, United States

Key Dates

Start Date

September 29, 2022

Primary Completion Date

August 31, 2026

Completion Date

August 31, 2027

Last Updated

June 5, 2025

Related Studies

RECRUITINGPhase 3

Efficacy of INM004 in Children With STEC-HUS

NCT06389474

Hemolytic-Uremic Syndrome

COMPLETEDPhase 2

An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome

NCT01194973

Atypical Hemolytic-Uremic Syndrome

COMPLETEDPhase 2

An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome

NCT01193348

Atypical Hemolytic-Uremic Syndrome

Haemolytic Uraemic Syndrome in Childhood: Clinical, Cognitive and Psychological Aspects

NCT01666548

Hemolytic-Uremic SyndromeChildren+2 more

Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4

NCT01406288

Hemolytic-uremic SyndromeEscherichia Coli Infections

Contacts

Study Manager

CONTACT

(801) 581-6410 hikostec@hsc.utah.edu

Sponsors

Lead Sponsor

University of Calgary

Collaborators

National Institute of Allergy and Infectious Diseases (NIAID)
Children's Hospital Medical Center, Cincinnati
Washington University School of Medicine
University of Utah
Seattle Children's Hospital
University of Colorado, Denver
Emory University
University of California, Davis
Baylor College of Medicine
Indiana University School of Medicine
University of Alabama at Birmingham
Arkansas Children's Hospital Research Institute
Children's National Research Institute
Children's Hospitals and Clinics of Minnesota
Medical University of South Carolina
University of Louisville
University of Oklahoma
Oregon Health and Science University
University of California, San Diego
McMaster University
The Hospital for Sick Children
University of Alberta
University of Kentucky
Case Western Reserve University
Nationwide Children's Hospital
Vanderbilt University Medical Center

Detailed Description

Full Eligibility Criteria

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: June 5, 2025Data synced to Clareo: April 28, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions