Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Multiple Dosing Regimens

Exclusion Criteria

• •1. Sex and Reproductive Status:
• •1. WOCBP who are unwilling or unable to use an acceptable contraceptive method or abstinence to avoid pregnancy for the entire study and for 60 days after the last dose of study drug
• •2. Women who are pregnant or breastfeeding
• •3. Women with a positive pregnancy test at screening or prior to study drug administration
• •2. Prohibited Medications:
• •1. Use of prophylactic migraine medication within 30 days prior to the Screening Visit.
• •2. History of use of analgesics (e.g., non-steroidal anti-inflammatory drugs \[NSAIDs\] or acetaminophen) on ≥ 15 days per month during the 3 months (12 weeks) prior to the Screening Visit.
• •3. Use of medication accepted for treatment of acute migraine for a nonmigraine indication on ≥ 15 days per month during the 3 months (12 weeks) prior to the Screening Visit.
• •4. Subjects who previously discontinued biologic migraine medication must have done so at least 6 months (24 weeks) prior to the Screening Visit.
• •5. Subjects taking a prohibited medication as defined per protocol