The Effect of Long-term Momordica Charantia Supplementation on Blood Glucose Levels

Exclusion Criteria

• •Use of medication/supplements that may influence the study results, such as metformin, gliclazide, glimepiride, tolbutamide, insulin, sitagliptin (DPP4 inhibitor), liraglutide (GLP-1 agonist), acarbose, repaglinide, pioglitazone, corticosteroids (systemically) , SGLT-2 inhibitors, (judged by our research physician)
• •Having a fasting glucose \>11.0 mmol/L
• •History of gastro-intestinal surgery or having (serious) gastro-intestinal complaints
• •History of liver dysfunction (cirrhosis, hepatitis) or liver surgery
• •Reported slimming, medically prescribed or other extreme diets
• •Reported weight loss or weight gain of \> 5 kg in the month prior to pre-study screening
• •Not willing to give up blood donation during the study
• •Current smokers
• •Alcohol intake ≥14 glasses (women) or \>21 glasses (men) of alcoholic beverages per week, on average
• •pregnant or lactating (self-reported)
• •Abuse of illicit drugs (soft- and hard drugs)
• •Food allergies for products that we use in the study
• •Participation in another clinical trial at the same time
• •Being an employee of the Food, Health \& Consumer Research group of Wageningen Food \& Biobased Research or dept. human nutrition and health of Wageningen University.