Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
The National Brain Mapping Laboratory (NBML)
With
University of British Columbia
Ruhr University of Bochum
Leibniz Research Centre for Working Environment and Human Factors
University of Tehran
Thirty schizophrenic patients will be recruited after meeting the inclusion criteria and will be randomly assigned to active and sham stimulation groups. A single session of concurrent prefrontal tDCS/fMRI will be conducted. Participants will undergo baseline task performance before the intervention. One week later, they will undergo the tDCS intervention (active or sham) next to the scanner during which they perform the working memory task varying in cognitive load. They will perform the task 24 h later again. They will be then transferred to MRI scanner right after stimulation
Age
18–50
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
men or women (18-50 yrs old) with a DSM 5 SCZ diagnosis,
If female, negative urine pregnancy test
significant cognitive impairment (1 SD below the norm on the working memory/executive functioning task performance)
feasibility for tDCS interventions according to safety guidelines
stable medication regime especially the classical neuroleptics and all CNS-activating medications, if taken, 4-6 weeks before the experiment
fluency in the native language
right-handed
ability to provide informed consent.
You may not be if
pregnancy
alcohol or substance dependence
history of seizure
history of neurological disorder
history of head injury
Presence of ferromagnetic objects in the body that are contraindicated for MRI of the head (pacemakers or other implanted electrical devices, brain stimulators, some types of dental implants, aneurysm clips, metallic prostheses, permanent eyeliner, implanted delivery pump, or shrapnel fragments) or fear of enclosed spaces). Eligibility will be determined by the "MRI Safety Screening Questionnaire" and verified, if necessary, by a radiology consultant.
