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Psychological Trauma and Resilience After ICU Stay in Patients Treated With Mechanical Ventilation for Severe Critical Illness: the Multicenter, Prospective, Observational RESIREA Study
Critically ill patients experience a severe physical disease, associated with a psychotrauma, which may lead to post-traumatic stress disorder (17 to 30% of patients after critical illness) and persistent symptoms of anxiety and depression. RESIREA study will study psychodrama, resilience and factors associated with resilience in patients previously included in the NUTRIREA-3 randomized controlled trial designed to compare standard calorie and protein feeding complying with guidelines to low-calorie low-protein feeding in a well-defined group of severely ill ICU patients requiring at least MV and vasoactive drugs.
Social demographic data (gender, age, marital status, psychological information and medical background) and medical data (severity of the disease, duration of ICU stay, SOFA score) will be collected, as for the NUTRIREA-3 trial. Before leaving the ICU, patient who agreed to participate to the NUTRIREA 3 study were asked to participate to the RESIREA study. Patients will be called by phone by a psychologist 3 months after their inclusion in the NUTRIREA-3 trial to complete the SF-36 score. Then, they will be asked to confirm their participation to the RESIREA study by completing four additional questionnaires (post-trauma stress disorder: IES-R; Resilience: CD-RISC; Social support: MSPSS; Perception of the disease: B-IPQ). If the patient does not respond to the phone call at the first time, he/she will be contacted again within a period of 2 weeks maximum (1 call/day). If the patient remains unreachable, he/she will be considered as lost for the study. Patients will be called again 12 months after their inclusion in the NUTRIREA-3 trial and will be asked to complete the five questionnaires (SF-36, IES-R, CD-RISC, MSPSS and B-IPQ). During this last phone call, 40 patients will be asked to a third interview by phone. These patients will be spotted thanks to their score at the IES-R and CD-RISC. This interview of 30 to 45 minutes will be planned within 15 days after the T12 call and recorded. This semi structured interview will be lead by an experienced clinical psychologist and follow 4 main topics : 1. Experience of ICU's 2. Perception of the disease or/and post intensive care disorders 3. Difficulties and capacities of coping 4. Difficult events in the patient's life
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
CHU Amiens Picardie nord
Amiens, France
CHU Amiens Picardie sud
Amiens, France
CHU Angers
Angers, France
CH Angoulême
Angoulême, France
CH Annecy Genevois
Annecy, France
CH Argenteuil
Argenteuil, France
CHU Jean Minjoz
Besançon, France
CH de Béthune
Béthune, France
CH Chartres Louis Pasteur
Chartres, France
CHU Gabriel Montpided
Clermont-Ferrand, France
Start Date
October 24, 2018
Primary Completion Date
March 16, 2021
Completion Date
December 16, 2021
Last Updated
January 14, 2022
200
ACTUAL participants
Lead Sponsor
Nantes University Hospital
NCT04419480
NCT07179276
Data Source & Attribution
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