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COMPLETEDNCT05191654

Investigation of Cardiopulmonary Parameters, Motor Development and Muscle Strength in DS With and Without CHD

Congenital heart diseases (CHD) are detected in 40-60% of individuals with Down syndrome (DS) and increase the risk of developmental delay in the presence of syndromes. The aim of the study was to com...

Lead sponsor: Atılım University•1 locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

Atılım University

Age

0 - 5 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Diagnosed with Down syndrome as a result of genetic analysis,
•For the congenital heart disease group; undergoing cardiac surgery at least 6 months before the evaluation, diagnosed as CHD by a pediatric cardiologist based on echocardiographic findings,
•For the group without congenital heart disease, patients who have not undergone cardiac surgery, are asymptomatic with a septal defect smaller than 4-5 mm, are expected to close, and are hemodynamically normal by a pediatric cardiologist,
•Children whose families were informed about the study and gave written consent to participate in the study were included in the study.

Exclusion Criteria

•Having another genetic abnormality other than Down syndrome,
•undergoing surgery other than cardiac surgery,
•Having an orthopedic or neurological problem,
•Respiratory support,
•With atlantoaxial instability,
•Children with hematological disease were not included in the study.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 13, 2022Terms

Trial snapshot

StatusCOMPLETED

Phase—

Enrollment28

Start dateOct 2020

Last updatedJan 13, 2022

Condition

Congenital Heart Defects Down Syndrome Gross Motor Development Delay

Locations shown

Atılım University

Ankara

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 13, 2022Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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