A Trial of HRS-8080 Tablets in Metastatic or Local Advanced Breast Cancer of Adults

Exclusion Criteria

• •1. For the case of symptomatic visceral metastasis, the investigators judged that it was not suitable to use relevant treatment;
• •2. patients with active brain metastasis (without medical control or with clinical symptoms), cancerous meningitis, spinal cord compression, or patients with a history of primary tumors of the central nervous system ;
• •3. History of clinically significant cardiovascular or cerebrovascular diseases;
• •4. The subject has one of many factors affecting oral drugs;
• •5. Active infection or fever with unknown cause \> 38.5 °C;
• •6. Active autoimmune diseases, History of immunodeficiency, including positive HIV serum test result and other acquired or congenital immunodeficiency diseases, or history of organ transplantation;
• •7. Known history of allergy to study drug ingredients.