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Lipoprotein Kinetics in T1D | Clinical Trials | Clareo Health

RECRUITINGNA

Lipoprotein Kinetics in T1D

Apolipoprotein C3-loading of Apolipoprotein B100 Lipoproteins and Cardiovascular Disease in Patients With Type 1 Diabetes

NCT05179954•University of Missouri-Columbia

View on ClinicalTrials.gov

Summary

The purpose of this research study is to understand how type 1 diabetes (T1D) increases the risk for cardiovascular diseases (heart attack and stroke). To this end, the investigators will compare apolipoprotein and triglyceride kinetics in people wtih T1D and healthy control participants.

Detailed Description

Not required

Eligibility

Age

18 - 45 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Age: ≥18 but ≤45 years
•premenopausal/eumenorrheic and not pregnant or breastfeeding
•non-obese (body mass index ≥18.5\<30.0 kg/m2)
•Fasting plasma triglyceride \<150 mg/dL
•Fasting plasma glucose \<100 mg/dL
•Plasma glucose 2 h after a 75 g oral glucose challenge \<140 mg/dL
•HbA1c \<5.6%.
•stable insulin regimen (multiple daily insulin injections or continuous subcutaneous insulin) for at least 8 weeks before screening
•no use of diabetes medications other than insulin
•HbA1c \<8.0%, basal (overnight fasted)
+1 more criteria

Exclusion Criteria

•more than 1.5 h of structured exercise/week
•use of tobacco products, excessive amounts of alcohol, or dietary supplements and/or medications known to affect lipid metabolism
•hypothyroidism or other disorders known to affect lipid metabolism
•conditions that would make it impossible to complete the study protocol

Locations (1)

University of Missouri School of Medicine

Columbia, Missouri, United States

Key Dates

Start Date

May 9, 2022

Primary Completion Date

December 31, 2026

Completion Date

December 31, 2027

Last Updated

February 10, 2026

Enrollment

ESTIMATED participants

Conditions

Type 1 Diabetes

Interventions

Metabolic testing

OTHER

Contacts

Amanda Heider

CONTACT

(573) 884-6852 ahmc4@health.missouri.edu

Mittendorfer Lab

CONTACT

MittendorferLab@umsystem.edu

Feasibility of a Tailored Online Self-compassion Intervention

NCT07051005

Type 1 Diabetes MellitusType 2 Diabetes Mellitus (T2DM)

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RECRUITINGNA

Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

NCT05188027

Type 1 DiabetesPost-menopause

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 10, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Lipoprotein Kinetics in T1D

Inclusion Criteria

Exclusion Criteria

Feasibility of a Tailored Online Self-compassion Intervention

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