This study is a multi-center prospective study. Patients who meet the indications for prostate puncture and whose PSA is in the gray area (4.0\~10.0 ng/mL) undergo standard prostate biopsy. The patient's serum was collected for PHI detection before puncture, and multi-parameter MRI was performed before puncture. To explore the sensitivity and specificity of PHI combined with PI-RADS score in the diagnosis of clinically meaningful prostate cancer. Assess the benefit of combining PHI and mpMRI before biopsy compared with phi or mpMRI alone. Formulate clinical recommendations for PHI and mpMRI.
Age
50–80
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Patients with suspected prostate cancer
Patients can perform standardized prostate biopsy
You may not be if
Have a history of prostate cancer
Use of drugs that affect PSA before blood sampling
