Mifepristone Outpatient Labour Induction

Exclusion Criteria

• •1. Breech presentation
• •2. Early labour
• •3. Contraindication to vaginal birth (placenta praevia, transverse lie, known or suspected cephalo-pelvic disproportion or other factor contraindicated to vaginal birth in the opinion of the investigator)
• •4. Fetal growth restriction with oligohydramnios and/or abnormal Dopplers
• •5. Presence of reduced fetal movements requiring urgent delivery, abnormal CTG or recent antepartum haemorrhage requiring immediate delivery
• •6. Medical conditions:
• •i. sexually transmitted infections (active infections only) ii. bleeding disorders, on anticoagulants, steroid or aspirin therapy iii. prior uterine operations (Caesarean Section or myomectomy)
• •7. Contra-indications to mifepristone including chronic adrenal, hepatic, renal failure
• •8. Hypersensitivity to mifepristone or to any excipients, or malnutrition
• •9. Severe asthma uncontrolled by therapy and inherited porphyria
• •10. Any investigational drug with an expected interaction with mifepristone which has been administered within 30 days prior to the trial drug administration.