Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Loxo Oncology, Inc.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Have been diagnosed with:
* CLL or SLL and have received treatment with the following five classes of therapy: Chemotherapy, anti-cluster of differentiation (anti-cd) 20 antibody, covalent Bruton's tyrosine kinase (BTK) inhibitor, B-cell lymphoma-2 (BCL-2) inhibitor, and phosphatidylinositol 3-kinase (PI3K) inhibitor
* MCL that has been previously treated with a covalent BTK inhibitor
* Richter's Transformation (RT) with previous Richter's directed-therapy
* Waldenstrom macroglobulinemia (WM), previously treated with chemotherapy, anti-CD20 antibody and a covalent BTK inhibitor
You may not be if
Inadequate organ function
Significant cardiovascular disease
History of allogenic or autologous stem cell transplant (SCT) or chimeric antigen receptor modified Tcell (CAR-T) therapy within 60 days
Tested positive for human immunodeficiency syndrome (HIV) or known active hepatitis B or C virus or cytomegalovirus (CMV) infection
Active, uncontrolled autoimmune cytopenia
Clinically significant active malabsorption syndrome
Participants requiring therapeutic anticoagulation with warfarin or another vitamin K antagonist
