Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Mayo Clinic
Age
40–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Diagnosis of knee OA by clinical criteria (American College of Rheumatology).
Identification of knee osteoarthritis by a radiologist on an existing knee radiograph obtained within 3 years of enrollment.
Moderate to severe knee pain for at least 3 months, defined as a score of ≥ 4 (on a 0-10 point numeric rating scale) in response to the question "What is the average level of your left/right knee pain in the past 3 months?".
You may not be if
Pregnancy.
Diabetes.
Anticoagulation therapy.
History of total knee replacement.
Prior knee prolotherapy or other regenerative product.
Any knee injection within 3 months.
Inflammatory (RA, gout, pseudogout etc.) or postinfectious knee arthritis.
Daily use of opioid medication.
Allergy or intolerance to study medication, corn allergy.
Body mass index (BMI) greater than 40 kg/m\^2.
Comorbidity severe enough to prevent participation in the study protocol.
Use of oral steroids during the study period
Use of injectable steroids in the past 3 months or during the study period
Clareo Health | Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis
