ALT-801 in Overweight and Obese Subjects With Type 2 Diabetes Mellitus (T2DM)

Inclusion Criteria

• •Written informed consent signed prior to the performance of any study procedures
• •Male or female volunteers, age 18 to 65 years, inclusive
• •Overweight to obese (BMI \>/=28.0 kg/m2)
• •Type 2 diabetes mellitus (T2DM), on stable regimen, for at least 3 months prior to screening, of any combination of (1) diet and exercise, (2) metformin with absent or mild gastrointestinal symptoms (nausea, vomiting or diarrhea), and/or (3) sodium glucose cotransporter-2 (SGLT-2) therapy
• •Female subjects of childbearing potential who are not pregnant or breastfeeding, do not plan to become pregnant during the study, and agree to use effective birth control