RC48 for Neoadjuvant Chemotherapy of HER2 Positive Breast Cancer

Inclusion Criteria

• •1. Enrolled were ≥ 18 years of age and \< 80 years of age
• •2. Female or male breast cancer
• •3. Patients with early or locally advanced breast cancer who are HER2-positive, have a tumor larger than 2 cm and/or have lymph node metastasis: HER2-positive is defined as 3 + by immunohistochemistry, or 2 + by immunohistochemistry, with a positive FISH test.
• •4. Left ventricular score ≥ 55%
• •5. ECOGPS score 0 or 1
• •6. Able to understand the test requirements, willing and able to comply with the test and follow-up procedures
• •7. Adequate organ function