Age

45–85

Sex

MALE

Healthy volunteers

Not accepted

Histologically proven initial diagnosis of adenocarcinoma of the prostate;
Clinical stage T1-4 N0 M0;
Prostatic assessment by multiparametric (mp) MRI;
Pelvic lymph node was assessed by PSMA PET/CT and mpMRI;
No distant metastasis was proven by PSMA PET/CT;
Patients may received neoadjuvant hormonal therapy;
45≤ Age ≤85;
Adequate performance status (ECOG 0-1);
No previous pelvic radiation therapy (RT);
No previous prostatectomy;
No previous invasive cancer (within 5 years before the prostate cancer diagnosis);
Ability to understand character and individual consequences of the clinical trial;
Written informed consent;

Carbon Ion Followed by Proton Radiotherapy for Prostate Cancer With Pelvic Lymph Nodes Metastases