National Institute for Health Research, United Kingdom
Age
18–any
Sex
MALE
Healthy volunteers
Not accepted
You may be eligible if
Confirmed pathogenic germline mutation in any of the following genes BRCA1, BRCA2, MSH2, MSH6, MLH1, PMS2, CHEK2, PALB2 or ATM.
Over the age of 18
Diagnosed with prostate cancer and at a time when staging imaging is clinically indicated; either:
* At a new diagnosis
* Biochemically progressing patients who were treated radically with surgery or radiotherapy (more than 6 months ago) and are currently not receiving hormonal treatment or chemotherapy
* Patients on active surveillance with a PSA doubling time of 6 months or less
You may not be if
Diagnosis of other malignancy (excluding basal cell cancer/squamous cell cancer of the skin) within five years of diagnosis
Known metastatic prostate cancer, both local and distant
Patients who have received any oncological treatment within the last six months
Patients on any investigational drug treatment
Patients on steroids
Known history of inflammatory/infective diseases (e.g. sarcoidosis, tuberculosis, inflammatory bowel disease)
Contraindications to having an MRI using the standard MRI checklist (e.g. pacemakers, aneurysm clips, claustrophobia)
