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Assessment of the Effect of Continuous Glucose Monitorization on Glycemic Variability and Insulin's Prescription in Hospitalized Patients With COVID-19
DM2 is a major comorbidity of COVID-19. It has been observed that subjects with DM2 require more medical interventions, have a significantly higher mortality (7.8% versus 2.7%) and injuries of multiple organs that the individuals not diabetics. In situations of glycemic variability, phenomena of oxidative stress and activation of protein kinase C can be initiated , through the release of pro-inflammatory cytosines , which could induce microvascular damage .Patients with diabetes and COVID-19 were shown to be more likely to develop serious or critical illness with more complications, and to have higher incidence rates of antibiotic therapy, non-invasive and invasive mechanical ventilation, and death (11.1% vs. 4.1%).
Age
18 - 100 years
Sex
ALL
Healthy Volunteers
No
National Institute of Medical Sciences and Nutrition Salvador Zubiran
Mexico City, Mexico
Start Date
June 1, 2020
Primary Completion Date
June 30, 2024
Completion Date
July 31, 2024
Last Updated
March 8, 2024
120
ESTIMATED participants
Lead Sponsor
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07480161