Loading clinical trials...

The Role of Genetic Factors in the Development of Bronchial Asthma in the Kazakh Population | Clinical Trials | Clareo Health

COMPLETED

The Role of Genetic Factors in the Development of Bronchial Asthma in the Kazakh Population

Preventive and Personalized Medicine (2021-2023)

NCT05088512•Asfendiyarov Kazakh National Medical University

View on ClinicalTrials.gov

Summary

To research for a genetic marker of bronchial asthma, a single nucleotide polymorphism (SNP) analysis of DNA obtained from the peripheral blood of patients with bronchial asthma and normal control will be performed.

Detailed Description

Unrelated Kazaks subjects who have bronchial asthma were recruited in the current study. Genotyping for various SNP associated due to the linkage disequilibrium patterns is to be performed. Genotypes would be statistically compared between patients with bronchial asthma and normal control subjects free of bronchial asthma

Eligibility

Age

5 - 65 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Persons with bronchial asthma confirmed by a doctor;
•The age of the patients is from 5 to 60 years;
•Persons of Kazakh nationality, whose paternal and maternal grandparents are Kazakhs.
•Persons who are able and willing to provide written informed consent;
•Persons capable and willing to comply with the research protocol;

Exclusion Criteria

•Persons who, in the opinion of the researcher, are mentally or legally incapacitated, which prevents obtaining informed consent;
•Pregnant or lactating women;
•Tuberculosis of any localization in the active phase and in history;
•Severe and decompensated diseases of the liver and kidneys, cardiovascular system;
•Severe and decompensated course of endocrine diseases;
•Autoimmune diseases;
•Systemic diseases;
•Oncological diseases;

Locations (1)

Kazakhstan

Almaty, Kazakhstan

Key Dates

Start Date

October 23, 2021

Primary Completion Date

January 20, 2023

Completion Date

January 20, 2023

Last Updated

March 14, 2023

Enrollment

300

ACTUAL participants

Conditions

Bronchial AsthmaGenome Wide Association Studies

Interventions

SNP analysis of the DNA

GENETIC

Behavioral Changes Among Asthmatic Children in Sohag Universty Hospital

NCT06624735

Bronchial Asthma

View study

ACTIVE_NOT_RECRUITINGPHASE2

Study of MG-ZG122 Humanized Monoclonal Antibody in Asthma Subjects

NCT07054034

Bronchial Asthma

View study

COMPLETEDPHASE3

BE Study of Albuterol Sulfate Inhalation Aerosol 90 mcg Per Actuation in Patients With Stable Mild Asthma

NCT06154304

Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 14, 2023Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions

The Role of Genetic Factors in the Development of Bronchial Asthma in the Kazakh Population

Inclusion Criteria

Exclusion Criteria

Behavioral Changes Among Asthmatic Children in Sohag Universty Hospital

Study of MG-ZG122 Humanized Monoclonal Antibody in Asthma Subjects

BE Study of Albuterol Sulfate Inhalation Aerosol 90 mcg Per Actuation in Patients With Stable Mild Asthma

the Effect of Use of Vit d and Probiotic as a Supplementaition in the Treatment of Bronchial Asthma in Patient Aged 6 to 50 Year and Its Effect in Decrasing Excerbation.

Echo and Electrocardiographic Findings in Children With Bronchial Asthma At Sohag University Hospital

Assessment of Bronchial Asthma Among Patients Attending Sohag University Hospital