Bezlotoxumab Versus FMT for Multiple Recurrent CDI

Inclusion Criteria

• •18-90 years old
• •diarrhea (3 or more unformed stools per 24h for two consecutive days; or \>= 8 unformed stools per 48h) XML File Identifier: KqQEbBLRYEZjGgsIl5GcI+NXCyM= Page 10/22
• •positive PCR test for toxin A/B genes and/or positive toxin EIA for current and previous episodes (low PCR cycle threshold value when only PCR performed)
• •a minimum of two prior CDI episodes
• •previous episode is maximum of 3 months prior to the current episode
• •the current episode responds well to Standard of Care treatment (vancomycin or fidaxomicin orally).
• •Assessment of the severity of the disease will be performed according to the ESCMID recommendations.
• •Both mild and severe CDI will be included