A Phase 1/2 Study to Determine Safety and Immunogenicity of Two COVID 19 Vaccines VB10.2129 (RBD Candidate) and VB10.2210 (T Cell Candidate) Previously Vaccinated in Healthy Adult Volunteers

Have had any acute illness with or without fever, within 72 hours prior to the first vaccination

Symptoms of upper respiratory infection, fever, persistent cough, shortness of breath, runny nose and breathing difficulties

Breastfeeding or who plan to breastfeed during the study

Have a known allergy, hypersensitivity, or intolerance to aminoglycosides

Had any clinically significant or chronic medical condition or any major surgery within the past 5 years which

Have any surgery planned during the study

Had any chronic use of any systemic medications, including immunosuppressant's, oral corticosteroids or other immune-modifying drugs, within the 12 months prior to Screening

Received any vaccination within the 28 days prior to Screening

Received any prescription medicines (except hormonal contraception for WOCBP) within 14 days prior to Visit 0 (Screening) or over the counter medicines (except paracetamol and acetaminophen at a dose of (≤2 grams/day)) within 48 hours of Visit 0.

Have a known history or a positive test of HIV 1 or 2, Hep B, or Hep C

Have a positive rtPCR test for SARS-CoV-2 within 2 days of Screening

Documented history of previous infection with SARS-CoV-2 and/or who have the presence of serum Ab indicative of a previous SARS-CoV-2 infection

Have a history of hypersensitivity or have had a serious reaction to a previous vaccination

Have any abnormality or permanent body art (eg, tattoo) that, would obstruct the ability to observe local reactions at the injection site.

Have a condition known to put them at high risk for severe COVID-19, including those with any of the following risk factors: Hypertension, diabetes mellitus, chronic pulmonary disease, asthma, chronic liver disease, known stage 3 or worse chronic kidney disease

Anticipating the need for immunosuppressive treatment within the next 6 months.

What this study is about