Finding studies
Finding studies
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Lead
University of Pennsylvania
With
This is a Phase I study evaluating the safety and feasibility of lentiviral transduced huCARTmeso cells when given in combination with VCN-01. Dose Finding Phase: This study was initiated using a 3+3 dose (de)escalation design in order to explore the initial safety of these drugs when given in combination, as well as to establish the recommended expansion dose of VCN-01 in this setting. Expansion Phase: The trial was expanded to include two parallel treatment arms further exploring the dosing sequence and schedule of these two investigational products when given in combination.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted