Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH)

Exclusion Criteria

• •Unstable hematoma defined as \> 6 mL increase as compared to previous CT volume taken at least 6 hours apart within 24 hrs after onset of ICH symptoms.
• •Anticipated neurosurgical evacuation by open surgery or minimally invasive surgery with or without Alteplase (EVD allowed).
• •Uncontrolled temp \>38.5˚C at enrollment.
• •Signs of intracranial infection or emergence of a systemic infection
• •Is pregnant or lactating
• •Signs of liver and kidney chronic disease (i.e. creatinine \>2, bilirubin \> 3, receiving dialysis)
• •Non-reversible bleeding diathesis
• •Used any chronic immunosuppressants or chronic anti-inflammatory drugs (excluding low-dose aspirin), by any route of administration within the past 7 days.
• •Anticipated withdrawal of life-sustaining therapies within the first week after admission.
• •In the opinion of the investigator, patient has any contraindication to the planned study assessments.
• •In the opinion of the investigator, patient has a condition that could interfere with the proposed treatment or unacceptably increase the individual's risk by participating in the study.
• •Concomitant enrollment in another acute interventional study