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Effect of Astaxanthin on the Patients With Alzheimer Disease

NCT05015374·1 site·ClinicalTrials.gov

What this study is about

Take this into the appointment.

Saves the questions and what to expect into your notes, next to the visit they belong to.

Keep this study

Lead

Kaohsiung Medical University Chung-Ho Memorial Hospital

With

China Medical University, China

This study aims to examine the benefit of Astaxanthin as adjuvant therapy for Alzheimer's disease.

Age

60–90

Sex

ALL

Healthy volunteers

Not accepted

You may be eligible if

1. 60 ≦ age ≦ 90
2. Clinical Dementia Rating Scale = 0.5 or 1
3. Under treatment with donepezil、rivastigmine or galantamine with good medical adherence
4. Get a signed informed consent from the patient or his/her family

You may not be if

1. Not using or poor medical adherence to donepezil、rivastigmine or galantamine
2. Combined using memantine or other cerebral perfusion enhancing agent, such as Piracetam, Dihydroergotoxine, Nicergoline etc.
3. New cerebrovascular disease happens during 3-year follow up
4. Mixed type dementia
5. Major psychiatric disease (such as depression, bipolar disorder, schizophrenia) or substance abuser (such as alcohol, illegal drug, hypnotics)
6. Heart failure, end stage renal disease, liver cirrhosis, or other major organ failure
7. Severe hearing impairment results in incomplete survey of neuropsychatric evaluation
8. No informed consent or no regular follow up

The record

StatusCompleted

PhaseNot applicable

Taking part46

StartedNov 2018

UpdatedSep 27, 2024

Where1

Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Taiwan