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Effect of Different Biomimetic Materials on White Spot Lesions in Enamel | Clinical Trials | Clareo Health

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Effect of Different Biomimetic Materials on White Spot Lesions in Enamel

NCT05001035•Benha University

Summary

This study will be conducted to evaluate: 1- The remineralizing effect of different biomimetic materials (Zinc carbonate hydroxyapatite nanoparticles, Poly-amido amine (PAMAM) and bioactive glass nanoparticles) on white spot lesions in enamel. 2- The clinical efficacy of these agents on disappearance of these white spots.

Eligibility

Age

15 - 25 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Total of 21 patients enrolled in this study will be selected having at least 4 teeth (one on each quadrant) which will be extracted for orthodontic treatment.
•These patients will be selected according to age groups between 15-25 years old
•good oral hygiene
•free of destroying habits for dental tissues

Exclusion Criteria

•Bruxism
•soft drinks consumption
•acid regurgitation, etc.).
•Selected teeth having any cracks, malformations, dysplasia or caries.

Locations (1)

Faculty of dental medicine for girls branch of Alazhar University

Cairo, Egypt

Key Dates

Start Date

July 1, 2021

Primary Completion Date

September 18, 2021

Completion Date

September 20, 2021

Last Updated

October 7, 2021

Enrollment

ACTUAL participants

Conditions

White Spot Lesion

Interventions

Time of assessment

OTHER

Resin Infiltration Vs Self-Assembling Peptide (P11-4) in Treating White Spot Lesions

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White Spot Lesion

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ACTIVE_NOT_RECRUITINGPHASE4

Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting

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White Spot LesionsWhite Spot Lesions [Initial Caries] on Smooth Surface of Tooth+1 more

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: October 7, 2021Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Effect of Different Biomimetic Materials on White Spot Lesions in Enamel

Inclusion Criteria

Exclusion Criteria

Resin Infiltration Vs Self-Assembling Peptide (P11-4) in Treating White Spot Lesions

Assessing the Effects of Resin Infiltration and Resin Modified Glass Ionomer on the Color Changes of White Spot Lesions in a Clinical and Laboratory Setting

Orthodontic Treatment on Oral Microbiota and Salivary Proteins

Remineralization Potential of PRG Barrier Coat Versus Fluoride Varnish in White Spot Lesions in Permanent Anterior Teeth of Children

Clinical Impact of White Tea and Wheat Grass on Color Enhancement of White Spot Lesions

Remineralization Effect Of Egg Shell Versus Fluoride Varnish On Early Carious White Spot Lesions In Primary Teeth