Loading clinical trials...
Loading clinical trials...
Brain Iron Toxicity and Neurodegeneration - An Ultrahigh Field (7T) MRI Study
A longitudinal observational neuroimaging study of individuals with Early Onset Alzheimer's disease during the prodromal phase, and matched control group - Ultrahigh Field MRI study at 7T
This study aims to determine whether high resolution MRI at 7T and Quantitative Susceptibility Mapping (QSM) can demonstrate a specific pattern of iron overload in strategically important areas of brain as a sensitive marker of pathological Alzheimer's disease i.e. patients with subjective or mild cognitive impairment associated with Amyloid or tau pathological state in the cerebrospinal fluid.
Age
18 - 75 years
Sex
ALL
Healthy Volunteers
No
Nottingham University Hospitals NHS Trust
Nottingham, East Midland, United Kingdom
Start Date
September 10, 2021
Primary Completion Date
March 1, 2025
Completion Date
March 1, 2025
Last Updated
March 21, 2024
40
ESTIMATED participants
MRI at 7T
OTHER
Lead Sponsor
Nottingham University Hospitals NHS Trust
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and ConditionsNCT06780917