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New Strategies for Pulmonary Assessment in Spinal and Chest Wall Deformity
Thoracic insufficiency syndrome (TIS) is a complex condition that involves chest wall deformities that can affect normal breathing and lung growth. In most cases, children with TIS are also born with spine disorders such as scoliosis. The inability of the thorax to support normal respiration or lung growth can cause respiratory distress and even mortality. Investigators aim to validate MRI imaging sequences to use as an assessment tool for pulmonary function.
Age
6 - 18 years
Sex
ALL
Healthy Volunteers
No
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Start Date
January 1, 2026
Primary Completion Date
August 30, 2026
Completion Date
August 30, 2026
Last Updated
March 5, 2026
Xenon-129
DEVICE
Lead Sponsor
Patrick Cahill, MD
Collaborators
Data Source & Attribution
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