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Generalized epilepsy is rarely reported in patients with Wilson disease (WD) and lacks experience in clinical practice. We aim to provide better experience for the diagnosis and treatment for WD patients with epilepsy in the future.
A retrospective study was performed in 13 Chinese WD patients with generalized epilepsy. Each patient was diagnosed with WD by clinical evaluation and genetic screening. Patients were given small doses of antiepileptic drugs (AEDs), followed by copper-chelation therapy when the seizures stabilized. Clinical manifestations, brain imaging changes, and treatment and outcome after a long-term follow-up were analyzed.
Age
All ages
Sex
ALL
Healthy Volunteers
No
Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Start Date
September 1, 2010
Primary Completion Date
September 1, 2017
Completion Date
March 1, 2019
Last Updated
July 16, 2021
13
ACTUAL participants
genetic test
GENETIC
Lead Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University
NCT06573723
NCT06425159
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07046507