Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Medstar Health Research Institute
With
Patty Brisben Foundation For Women's Sexual Health
Society of Gynecologic Surgeons
Age
18–any
Sex
FEMALE
Healthy volunteers
Not accepted
You may be eligible if
Women ≥ 18 years old with biopsy confirmed or clinically diagnosed+ LS
English-speaking or Spanish-speaking
Electing to undergo Fractionated CO2-laser therapy
Willing and able to undergo concomitant 0.05% clobetasol propionate treatment
You may not be if
Prior surgery with placement vaginal mesh for repair of pelvic organ prolapse (does not include vaginal mesh for anti-incontinence procedure "sling" or prior mesh sacrocolpopexy)
Prior laser, topical immunomodulators or systemic therapy for LS
Active genital infection\^
Suspicious vulvar lesion that has not been evaluated
Known vulvar or vaginal malignancy or active treatment for other malignancy
Planning pregnancy or pregnant
Prior pelvic radiation therapy
Topical corticosteroid use on the vulvovaginal tissues in the past 2 weeks\*
Contraindication or allergy to clobetasol propionate 0.05%
Currently breast-feeding or lactating
History of poor wound healing, keloids or hypertrophic scarring
History of a skin condition that could interfere with evaluation of efficacy and safety
* Eligible for inclusion after washout period of 2 weeks \^Eligible for inclusion after treatment. For patients with known genital HSV we will instruct them to remain on suppression for the duration of the study.
Clareo Health | Fractionated CO2 Laser With and Without Clobetasol for Treatment of Vulvar Lichen Sclerosus
