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Reflex Excitability in Post-stroke Stiff-Knee Gait | Clinical Trials | Clareo Health

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Active Not RecruitingNANCT04947865

Reflex Excitability in Post-stroke Stiff-Knee Gait

The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait. We use electrical stimulation of the peripheral nerve...

Lead sponsor: MetroHealth Medical Center•1 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

MetroHealth Medical Center

Collaborators

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

The purpose of this study is to investigate the role of hyperreflexia in post-stroke Stiff-Knee gait function. In one aim,

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Aged at least 18
•Premorbidly independent
•If post-stroke, mild to moderate impairment determined by standard practices per the physical therapist
•Able to continuously walk for 30 minutes
•If post-stroke, reduced knee flexion during walking relative to unimpaired side
•If post-stroke, hemiparesis
•Ability to provide informed consent

Exclusion Criteria

•No history of serious lower limb musculoskeletal injury
•No functionally relevant osteoarthritis and weight-bearing restrictions
•No functionally relevant polyneuropathy
•No functionally relevant cognitive impairment
•No functionally relevant vision impairment

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 19, 2025Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhaseNA

Enrollment60

Start dateJun 2021

Last updatedDec 19, 2025

Condition

Stroke Chronic Stroke Gait, Hemiplegic Gait, Spastic Gait Disorder, Sensorimotor+2 more

Locations shown

MetroHealth Medical Center

Cleveland, Ohio

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 19, 2025Data synced to Clareo: May 3, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions