Optimal Encephalitis/Meningitis Roadmap Via Precise Diagnosis and Treatment

Inclusion Criteria

• •Patients with suspected meningitis : the patient has a new fever (\>38.5℃), accompanied by ≥1 of the following manifestations：
• •1. Stiff neck
• •2. Change in state of consciousness
• •3. Other signs of meningitis: such as meningeal irritation.
• •Patients with suspected encephalitis: Unexplained changes in the state of consciousness for more than 24 hours (including lethargy, agitation, personality changes, etc.) or accompanied by recent memory impairment, with the following ≥1 manifestations:
• •1. Fever during the course of the disease (≥ 38℃); (oral temperature)
• •2. Convulsions or focal neurological symptoms;
• •3. Increase in the number of cerebrospinal fluid cells (\>4\*10\^6/L);
• •4. Abnormal EEG that meets the manifestations of encephalitis and cannot be attributed to other reasons
• •5. Imaging suggests encephalitis (CT or MRI)
• •Have not received effective anti-infective treatment yet
• •Have an identifiable address and live in the area during treatment.
• •Suspected encephalitis/meningitis patients who are willing to participate in trial treatment and follow-up and can give informed consent (if the subject is illiterate, sign or hearing consent is required).
• •Willing to comply with follow-up research procedures.