Patients attended the sites in accordance with routine clinical practice. It is assumed that visits will be conducted every 3-4 months. Patients underwent standard procedures and tests according to clinical guidelines and physician's judgement. Available data from routine clinical management of the patients was collected at patients' visits to the clinical site. Patients enrolled in the study were followed up until death or study close whichever occurred first. The recruitment period was planned for 24 months, observation period for maximum of 24 months, with total duration of study 4 years. Patients could discontinue from this NIS at any time.
