Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Medical University Innsbruck
Age
18–50
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. DSM-5 diagnosis of Major Depressive Disorder (MDD) without psychotic features (296.22, 296.23, 296.32, 296.33) made through the Structured Clinical Interview for the DSM-V (SCID-V).
2. MADRS score ≥ 25
3. Pharmacologically treatment-resistant depressive episode \[Stage ≥ II, defined by Thase \& Rush (1997): failure of at least 2 adequate trials of at least 2 distinctly different classes of antidepressants (≥ 4 weeks each)\] (88).
4. Age: 18 - 50 years
5. Written informed consent
You may not be if
1. Participation in another interventional clinical trial
2. Relative contraindications to ECT treatment in accordance with the consensus paper of the Austrian Society of Psychiatry and Psychotherapy:
4. Contraindications to the conduction of MRI
5. History of one or more of the following diagnoses (DSM-5):
* MDD, single or recurrent episode with psychotic features (296.24; 296.34)
* past or current substance dependence (except caffeine, nicotine) (303.x, 304.x, 305.x)
