Xiao-yong Man

CONTACT

Lead Sponsor

Second Affiliated Hospital, School of Medicine, Zhejiang University

Age

18 - 75 years

Sex

ALL

Healthy Volunteers

No

•1.18 to 75 years of age 2.Moderate to severe chronic psoriasis, BSA≥3% 3.Duration of psoriasis≥6 months 4.Patients must be candidate for systemic therapy or phototherapy 5.No contradiction to Etanercept 6.Informed consent must be obtained 7.For female, ß-hCG test is negative and contraception is accepted

•1. Diagnosis of pustular psoriasis, erythroderma psoriasis or drug-induced psoriasis
•2. Having severe infections, including hepatitis, HIV and tuberculosis
•3. No live vaccines 12 weeks before enrollment, through the study and 1 year after the last dose of Etanercept
•4. Having significant allergies to biological agents
•5. Having the previous experience of biologics
•6. Having a history of malignancy
•7. Having contradictions to Etanercept
•8. Refusal of contraception
•9. Having serious or unstable/uncontrolled illnesses