Finding studies
Finding studies
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Lead
NMD Pharma A/S
With
The study is a cross-sectional pilot study and will be led by investigators: 1. Professor Brian Clark, PhD, Ohio University 2. Professor William David Arnold, MD, Ohio State University Up to 16 older (\>70 yrs.) individuals and 8 healthy younger (18-50 yrs.) individuals will be included in this cross-sectional pilot study. To assess whether clinically meaningfull muscle weakness is associated with NMJ transmission failure, results from single fiber EMG analyses and repetitive nerve stimulation in older individuals with clinically meaningfull muscle weakness will be compared to those obtained in older adults without muscle weakness and with healthy young individuals. To assess whether NMJ transmission deficits correlates with different measures of functional capacity, a series of different functional tests will be performed.
Age
18–any
Sex
ALL
Healthy volunteers
Accepted