Impact of Early Ventilation in Stroke Outcomes in Patients With Sleep Apnea After First Ever Stroke

Exclusion Criteria

• •1. CSA with Left Ventricular Ejection Fraction ⩽45%.
• •2. Ventilation treatment for sleep apnea diagnosis, prior to stroke.
• •3. Risk of aspiration.
• •4. Nasogastric feeding tube.
• •5. Transient ischemic attack, hemorrhagic stroke or subarachnoid hemorrhage.
• •6. Stroke due to a secondary cause (e.g. vascular malformation, vasculitis, brain tumor, head trauma, or predisposition to bleeding).
• •7. Cardiorespiratory distress.
• •8. Advanced chronic lung disease requiring supplemental oxygen.
• •9. Concomitant central nervous system diseases such as dementia or multiple sclerosis.
• •10. Uncontrolled psychosis or agitation.
• •11. Glasgow Coma Scale (GCS) score \<10 at screening.
• •12. Anosognosia, global or Wernicke aphasia.
• •13. Insufficient upper limbs function to use a mask and no overnight caregiver to help.
• •14. Inability to attend to the rehabilitation program of the hospital.
• •15. Pregnant and breast-feeding women.
• •16. Participation in another clinical study (except a standard-of-care registry).
• •17. Any other condition that, according to the Investigator, renders the subject unsuitable for ventilation.