Postoperative Noninvasive Ventilation After Upper Abdominal Surgery in Chronic Obstructive Lung Disease

NCT04877353•South Valley University

Summary

In Qena university hospital a prospective, randomized study was carried out on 100 COPD patients, all were divided into; conventional therapy without NIV (C group) 50 patients or with prophylactic NIV(N group) 50 patients.NIV applied for approximately 30 to 45 min at 2- to 4-h intervals for 48 h following surgery . Primary endpoint was the acute respiratory events (ARE) .Secondary endpoints were acute respiratory failure (ARF), intubation rate, mortality rate, infectious and non-infectious complications, and ICU stay.

Eligibility

Age

18 - 75 years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•* Age˃18 years, scheduled for upper abdominal surgery under general anesthesia.
•* Moderate to very severe COPD (GOLD II to IV).
•* ASA functional status II or greater.

Exclusion Criteria

•* Contraindications to the application of NIV.
•* Sleep apnea syndrome.
•* Facial deformation.
•* Inability to follow the study.

Locations (1)

asmaa Mostafa

Luxor, Egypt

Key Dates

Start Date

January 1, 2019

Primary Completion Date

March 30, 2020

Completion Date

November 15, 2020

Last Updated

May 7, 2021

Enrollment

100

ACTUAL participants

Conditions

Acute Respiratory Failure Post Surgical (Diagnosis)

Interventions

NIV

DEVICE