Finding studies
Finding studies
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Lead
University of Minnesota
Participants will be recruited from ongoing studies will some recruitment of tobacco users and non-smoking controls outside of ongoing studies. In this prospective, cohort study of various tobacco users and non-smokers, a punch biopsy model of wound healing will be used to determine the effects of various tobacco products on inflammatory response and oxidative stress response to wounding: 1. Clinical wound inflammation as assessed by: 1. Thermography, 2. Clinical assessment, 3. Laser Doppler Technologies, 4. Transcutaneous oxygen assessment 2. Biological wound inflammation as assessed by: 1. Cytokine profiles, 2. Histology, 3. Genetic assessment, 4. Epigenetic evaluation 3. Systemic inflammation as assessed by: 1. Biomarkers, 2. Cell counts
Age
18–any
Sex
ALL
Healthy volunteers
Accepted