Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Guy's and St Thomas' NHS Foundation Trust
Age
18–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Age ≥ 18 years
BMI \<30 kg/m¬2
Confirmed diagnosis of COPD
Currently using domiciliary NIV with average reported compliance of at least 3hours
Ability to provide informed consent
Medical stability confirmed by recruiting physician
Free of exacerbations for at least 2 weeks prior to enrolment
Presence of expiratory flow limitation on forced oscillation technique criteria
Age ≥ 18 years
No expiratory flow limitation on forced oscillation testing
No acute illness on study day
Ability to provide informed consent
You may not be if
Current acute illness as determined by recruiting physician e.g. upper respiratory tract infection
Presence of major medical comorbidity, e.g. severe heart failure (LVEF \<30%), active malignancy, end-stage renal failure (CKD 4), and neuromuscular disease
Subjects who have had surgery of the upper airway, nose, sinus, or middle ear within the previous 90 days.
Psychosocial factors that would prevent compliance with study protocol
Clareo Health | Efficacy of an Advanced Auto-titrating NIV in COPD
