Xin Wang, MD

CONTACT

Lead Sponsor

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•≥18 years；
•Esophageal or Esophagogastric cancer；
•Histologically proven squamous cell carcinoma or adenocarcinoma in patients staged as I-IVa (AJCC 8th)；
•Primary treatment performed in Cancer Hospital, Chinese Academy of Medical Sciences；
•ECOG PS score: 0\~1；
•Estimated survival time ≥3 months；
•Normal organ and marrow function as defined below:Hemoglobin: greater than or equal to 100g/L ;Leukocytes: greater than or equal to 4,000 G/L; Neutrophil: greater than or equal to 2,000 G/L; Platelets: greater than or equal to 100,000/mm3 ; Creatinine: less than or equal to 1.5 times the upper limit or CCR greater than or equal to 60 ml/min; AST/ALT: less than or equal to 2.5 times the upper limit; Total bilirubin: less than or equal to 1.5 times the upper limit; INR: less than or equal to 1.5 times the upper limit; APTT: less than or equal to 1.5 times the upper limit; PT: less than or equal to 1.5 times the upper limit；
•Informed consent；

•With any distant metastasis out of regional lymphatic drainage or in liver, lung, bone, CNS, etc；
•Patients with other cancer history in 5 years except cervical carcinoma in situ and non-malignant melanoma skin cancer；
•Existing active infection such as active tuberculosis and hepatitis；
•History of myocardial infarction within the past 6 months or history of ventricular arrhythmia；
•Uncontrolled illness including, but not limited to, active infection, symptomatic heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness History of allergic reactions attributed to paclitaxel, albumin or cisplatin；
•Participation in other clinical trials currently or within 4 weeks of selection；
•Pregnant or lactating females；
•Absence of medical records.

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