Study of PD-1 Antibody Combined With Chemoradiotherapy in Oligometastatic Esophageal Cancer

Exclusion Criteria

• •Pregnancy, possible pregnancy, or breast-feeding;
• •Psychological, family, social and other factors lead to uninformed consent;
• •An esophageal mediastinal fistula and/or an esophageal tracheal fistula prior to treatment;
• •Serious complications such as ischemic heart disease, arrhythmias, or other types of heart disease requiring treatment; liver cirrhosis; interstitial pneumonia or pulmonary fibrosis; active gastrointestinal bleeding; mental disorders being treated with antipsychoticagents or requiring treatment;
• •Controlled diabetes mellitus;
• •A history of autoimmune disease, autoimmune disease (such as colitis, hepatitis, hyperthyroidism, including but not limited to these disease or syndrome) and a history of immune deficiency, including test positive for HIV, or has other acquired, congenital immunodeficiency disease, or have a history of organ transplantation and the history of allogeneic bone marrow transplantation;
• •A history of interstitial lung disease and a history of non-infectious pneumonia;
• •Active hepatitis B (HBV DNA ≥ 2000 IU/mL or 104 Copies /mL), hepatitis C ;(positive HCV antibody and HCV-RNA above the detection threshold of the assay）
• •Any situation that is unstable or may compromise patient safety and compliance ;
• •Active infections, such as active tuberculosis, are present;