Nonavalent HPV Vaccine in the Treatment of Difficult-to-treat Palmo-plantar Warts

Exclusion Criteria

• •Suspicion of COVID, with confirmation by autotest.
• •Any causes of immunosupression: organ transplant recipients, bone-marrow transplantation, immunosupressive regimens for any diseases, HIV positivity.
• •Women or men who received HPV Vaccine previously of the study;
• •Any serious chronic or progressive disease according to the judgement of the investigator;
• •Individuals with history of known allergies/hypersensitivity to any component of study vaccine;
• •Individuals who have any malignancy or lymphoproliferative disorder;
• •Individuals with thrombocytopenia or coagulation disorder contre-indicating intramusculary injections;
• •Patient with anticoagulant therapy
• •Individuals with body temperature \> 38.0 degrees Celsius or/and acute disease within 3 days of intended study vaccination;
• •Women who are pregnant or are breast-feeding, or are of childbearing age who have not used or do not plan to use acceptable birth control measures, during the first 6 months ½ of the study;
• •Individuals under a measure of legal protection or unable to consent;
• •Individuals participating in any clinical trial with another investigational product 28 days prior to first study visit or intent to participate in another clinical study at any time during the conduct of the study.
• •Participation in another interventional study involving human participants or being in the exclusion period at the end of a previous study involving human participants, if applicable
• •Patient on AME (state medical aid) (unless exemption from affiliation).
• •Patient wishing to be vaccinated with Gardasil 9® within 6 months or refusing the principle of postponing vaccination.
• •Immunosuppressive therapy including use of systemic corticosteroids or chronic immunosuppressant medication (more than 14 days)