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Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia | Clinical Trials | Clareo Health

ACTIVE_NOT_RECRUITINGNA

Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia

NCT04783571•Massachusetts General Hospital

Summary

The investigators will test the hypothesis that auditory stimulation (playing quiet sounds during sleep) can normalize brain activity during sleep and improve memory in patients with schizophrenia. The investigators will do this by measuring sleep and memory performance under two conditions separated by one week: receiving auditory stimulation during sleep and not receiving auditory stimulation during sleep. The investigators will study healthy subjects and outpatients with schizophrenia.

Eligibility

Age

18 - 50 years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•For healthy controls:
•Male and female subjects
•18-50 years of age
•Proficient in English
•For schizophrenia patients:
•Male and female schizophrenia outpatients
•18-50 years of age
•Proficient in English
•Able to give informed consent

Exclusion Criteria

•Pregnant females
•Current use of psychotropic medications (healthy controls only)
•A history of head injury resulting in prolonged loss of consciousness or other neurological sequelae
•IQ \<85
•Neurological disorder (including seizure disorder)
•Significant hearing or vision loss
•Current substance abuse or dependence (nicotine abuse or dependence is not exclusionary)
•Any unstable chronic medical condition that affects sleep
•Diagnosed sleep disorder

Locations (1)

Massachusetts General Hospital

Boston, Massachusetts, United States

Key Dates

Start Date

April 13, 2020

Primary Completion Date

December 31, 2025

Completion Date

December 31, 2025

Last Updated

January 14, 2025

Enrollment

ESTIMATED participants

Conditions

Schizophrenia

Interventions

Placebo

OTHER

Auditory Stimulation

OTHER

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 14, 2025Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia

Inclusion Criteria

Exclusion Criteria

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