1. Laser trabeculoplasty other than selective laser trabeculoplasty (SLT)

2. History of iStent or iStent inject within 180 days of the screening visit

3. History of ECP or Micropulse laser

4. Trabeculectomy or other bleb forming procedure including Xen, Express and glaucoma drainage device/valves

5. Prior canaloplasty (ab interno and ab externo)

6. Prior goniotomy or trabeculotomy

7. History of Hydrus microstent or suprachoroidal stent

8. History of cataract surgery within 6 months of screening

9. Acute angle closure, traumatic, congenital, malignant, uveitic or neovascular glaucoma, pigmentary or pseudoexfoliative glaucoma

Multicenter Ab-interno Glaucoma Study Investigating Canaloplasty