* Sickle cell disease is the most common inherited disease of the red blood cell
* During sickle cell disease, the decrease in Bone Mineral Density (BMD) in children is very common: 19 and 56% depending on the studies
* children with sickle cell disease have an increase in resting energy expenditure of 15-20%
* children with sickle cell disease have a significant decrease in muscle mass
* there are no specific nutritional recommendations for sickle cell disease in children
Our main purpose is to assess the effects of an increase in nutritional intake on the bone mineral density of children with sickle cell disease, for 12 months
Our secondary objectives are :
1. / Evaluate the effects of an increase in nutritional intake on: body composition, height and weight growth, frequency of complications of sickle cell disease, school absenteeism, cardiac function, cerebral vasculopathy, biological parameters follow-up, and the relationship with the treatment started
2. / Creation of a sero-type blood bank for future research
